Research Interests
 

The main interests of the group are to dissect the mechanisms and factors that control somatic cell reprogramming and tissue regeneration in mammals. Computational approaches are employed to identify the key regulators and mechanisms underlying retinal regeneration in mammals and to translate these fundamental discoveries into applications such as cell therapies for retinal degeneration. An additional focus of the group is the study of chromatin organization and 3D genome folding in somatic, stem, and cancer cells, using an integrated and innovative methodology that combines state-of-the-art super-resolution microscopy with genomic approaches. AI-driven and computational methods are applied to analyze super-resolution imaging data in order to elucidate, identify, and reconstruct the biological functions observed in cells, tissues, and organs.